PUBLICATION

Bio-integrated Electronics Lab.

Journal

2025 Vialess heterogeneous skin patch for multimodal monitoring and stimulation

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작성자 최고관리자 작성일 25-01-22 17:48

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Author
Hyeokjun Lee, Soojeong Song, Junwoo Yea, Jeongdae Ha, Saehyuck Oh, Janghwan Jekal, Myung Seok Hong, Chihyeong Won, Han Hee Jung, Hohyun Keum, Sangyoon Han, Jeong Ho Cho, Taeyoon Lee, Kyung-In Jang
Journal
Nature Communications
Vol
volume 16, Issue 1
Page
650
Year
2025
DOI
10.1038/s41467-025-55951-6

Abstract

System-level wearable electronics require to be flexible to ensure conformal contact with the skin, but they also need to integrate rigid and bulky functional components to achieve system-level functionality. As one of integration methods, folding integration offers simplified processing and enhanced functionality through rigid-soft region separation, but so far, it has mainly been applied to modality of electrical sensing and stimulation. This paper introduces a vialess heterogeneous skin patch with multi modalities that separates the soft region and strain-robust region through folded structure. Our system includes electrical and optical modalities for hemodynamic and cardiovascular monitoring, and a force-electrically driven micropump for drug delivery. Each modality is demonstrated through on-demand drug delivery, flexible waveguide-based PPG monitoring, and ECG and body movement monitoring. Wireless data transmission and real-time measurement validate the feedback operation for multi-modalities. This engineered closed-loop platform offers the possibility for broad applications, including cardiovascular monitoring and chronic disease management.